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In this Perspective, we describe the distribution and chemical changes that occur as SHS is transformed into THS, studies of environmental contamination by THS, human exposure studies, toxicology studies using animal models and in vitro systems, possible approaches for avoiding exposure, remediation of THS contamination, and priorities for further research

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In-Market Sales : In-market sales, or IMS, is defined as sales to the retail channel, depending on the market and distribution model

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