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Rapid weight loss can signal energy deficiency to the hypothalamus, suppressing gonadotropin-releasing hormone (GnRH) and subsequently reducing luteinising hormone (LH) and follicle-stimulating hormone (FSH)
This is crucial, given that obesity is a significant risk factor for various health issues, including heart disease, stroke, and diabetes
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Monitoring during transition During titration, pharmacists should provide structured follow-up via telephone, face-to-face or digital check-ins, as well as encourage the use of adherence aids (e.g
doi: 10.1113/jphysiol.2008.164012
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