can you take semaglutide if you've had your gallbladder removed Navigating Use After Removal – PlexusDx Semaglutide without a Gallbladder :

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To understand the efficacy of this medication, one must first ask: how does semaglutide work within the human body

Peripheral infusion of GLP-1 decreases food consumption and increases satiety in both normal and obese individuals, presumably by interaction with sensory neurones in the gastrointestinal tract or hepatoportal region (Trapp and Brierley 2022)