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GLP-1 medications interact with receptors in both the gut and the brain

However, as its usage surges, so does the importance of understanding its potential side effects

It suppresses IL-6 and TNF- production while enhancing IL-10 production in macrophages, and inhibits the mTOR/STAT3 pathway in T cells, thereby reducing proinflammatory Th17 cells and cytokines such as IL-17 and IL-22, while promoting regulatory T-cell (Treg) differentiation (21)