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Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States

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In oral squamous cell carcinoma, erianin exerts anticancer effects through a dual mechanism: Erianin blocks the cell cycle in the G2/M phase, activates the apoptosis program and regulates autophagy (34) and induces autophagy-dependent apoptosis by inhibiting the palmitoyl-protein thioesterase 1/mTOR signaling pathway (35) and regulating the MAPK pathway (36)

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These findings suggest that this PLGA-based nanosystem offers a novel and effective strategy for sustained PD therapy, improving patient outcomes by addressing both motor symptoms and therapy-induced side effects 124