The incretin effect is reduced in people with type 2 diabetes (6)
99 Literature shows that mostly T2D has been found to be linked with elevated risk for various cancers like the pancreas, liver, breast, colorectal, endometrium, and bladder
The most common side effect with this new medication like many medications is mild nausea, and it is not a stimulant, so those patients that have not been able to tolerate Phentermine or similar medications can take a GLP-1 medication alone to help with their appetite
Clinical trials demonstrate that patients using semaglutide maintain weight loss more effectively than those using diet and exercise alone, with benefits extending to cardiovascular outcomes and diabetes risk reduction
Similarly, the discovery of a RAAS chronobiology could represent a milestone to change the paradigm of treatment of these pathologies