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Captured mAb variants were detected by an APconjugated polyclonal anti-human IgG Fc specific Ab from goat (Sigma-Aldrich, A9544) (diluted 1:5000 in PBS/T/S) and visualized by addition of p-nitrophenylphosphate (Sigma-Aldrich) (10 g/mL in diethanolamine buffer)

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Consult your physician if constipation persists beyond 2 weeks or if you experience severe abdominal pain, vomiting, or inability to pass gas

PIT is particularly effective for neuropathic pain, complex regional pain syndrome, and patients with widespread chronic pain that has not responded to conventional treatment