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In lean models with normal NAD+ homeostasis, NNMT inhibition may produce minimal metabolic shifts

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Similar secondary IgM-mediated autoimmune responses have been observed to target various oxidation-specific epitopes, such as MDA, azelaic acid, phosphatidylinositol, S-farnesyl-L-cysteine, and membrane anchorage molecules such as myristic and palmitic acid [138]