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academic.oup.com/jes/article/9/ GLP-1 in addiction medicine: GLP-1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward/stress hubs (VTA, NAc, ARC, PFC, hypothalamus)
In 2015, triple agonists simultaneously targeting the GLP-1R, GCGR, and GIPR were also developed, whose weight loss in mice exceeded those of the dual agonists [26]
The figures were created with the assistance of Figdraw ( Ethics declarations Competing interests The authors declare no competing interests
Kavuru MS
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