Rapeseed oil is composed mostly of C16-18 fatty acids that the Malassezia species can metabolize, making it a potential trigger for fungal acne
For authorised medicines, the MHRA requires manufacturers to provide evidence-based storage instructions on the product label, in the SmPC (intended for healthcare professionals), and in the PIL (intended for patients)
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Future large-scale, well-designed clinical trials will be essential to confirm their therapeutic potential, clarify the contribution of metabolic versus immunological effects, and define their role within the treatment algorithm of PsO and PsA