The possible chemical equations for preparing the Ag-NPs are: After dispersion of silver ions in the aqueous solution of GSH matrix (Equation 1), GSH reacted with the Ag + to form a GSH complex [Ag(GSH)] + , which reacted to form [Ag (GSH)] (Equation 2)
However, sustained high doses, overdose, fasting, alcohol use, or pre-existing liver disease can overwhelm glutathione reserves, increasing risk of hepatotoxicity and oxidative stress
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The strongest evidence supports its role in skin repair and wound healing
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