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17 The UKPDS also demonstrated that metformin is associated with less weight gain and fewer hypoglycemic episodes compared with sulfonylureas

It appears that certain pathways of carnitine metabolism, such as the acetylation of carnitine to acetyl-carnitine, are impaired, possibly as a result of the toxicity of antiretroviral medication

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En su conjunto, estos resultados, aun cuando no son concluyentes, encuentran sustento en los hallazgos previos demostrados en otros modelos animales, demostrando su importancia en el esclarecimiento del posible efecto beneficioso del suplemento alimentario con L-carnitina en humanos que sufren alteraciones metablicas del tipo de las dislipidemias en asociacin con el consumo de dietas hipercalricas