Several case reports have linked the use of these drugs, mainly exenatide, with the occurrence of acute kidney injury, primarily through hemodynamic derangement due to nausea, vomiting, and diarrhea [28]
Our full walkthrough on how to keep the weight off after a GLP-1 and avoid regain once you stop or taper lays out exactly how to plan for that
Volume depletion and hypotension can occur with SGLT2 inhibitors due to osmotic diuresis, particularly in elderly patients, those taking diuretics, or individuals with impaired renal function
It has been demonstrated that a component derived from the Leonotis sibiricus plant can boost insulin production in INS-1E cells while simultaneously promoting cell proliferation (133)
On a different level, GLP-1RAs reduce the concentration of angiotensin II (Ang II), which lowers arterial hypertension in T2DM and improves systemic insulin sensitivity ( 4.3 Gastrointestinal effects The gastrointestinal (GI) tract is greatly impacted by GLP-1RAs