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Tesamorelin/Ipamorelin : Tesamorelin is a GHRH analogue that has FDA approval for reduction of visceral fat in HIVassociated lipodystrophy, and is being explored more broadly for visceral fat and metabolic changes related to aging

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PubMed pubmed.ncbi.nlm.nih.gov [54] Semaglutide for the treatment of obesity PubMed pubmed.ncbi.nlm.nih.gov [55] Value of GLP-1 receptor agonists versus long-acting insulins for type 2 diabetes patients with and without established cardiovascular or chronic kidney diseases: A model-based cost-effectiveness analysis using real-world data ScienceDirect science/article/abs/pii/S0168822723001006

Medications, notably opioid pain relievers, can cause secondary constipation, particularly in the elderly