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JAMA 282:15681575 Clemmensen C, Chabenne J, Finan B et al (2014) GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet

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1 Introduction With an aging global population, it is estimated that 2.2 billion people worldwide are suffering from visual dysfunction, which severely impedes the individuals quality of life and poses threats to public health ( Ferroptosis, a term initially coined by Dixon in 2012, is a distinctive form of RCD featured by the iron-dependent lethal aggregation of lipid peroxides located at the cell membrane ( Figure 1 )

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[2] Current clinical guidance from the American Diabetes Association acknowledges this uncertainty, recommending that healthcare providers remain vigilant for pancreatitis symptoms but not avoid GLP-1 receptor agonists solely based on theoretical pancreatic concerns

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And longer lifespans due to the use of GLP-1s mean more years of consumption overall

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Department of Psychology, College of Arts and Sciences, East Carolina University, Greenville, NC

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