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Why is it important not to shake the vial during reconstitution

Mine have changed in the frequency, I used to be bang on 28 day cycle before injections, now it's sometimes 35 days

To be totally honest with you, I cannot remember what effects the Gabapentin had on me, I tried it, along with most other things for a while before the Oxycontin & it did nothing to help relieve the pain in my back, neither did the other drugs