www.pubmed.gov glutathione SYNTHESIS Glutathione: Master Antioxidant, Reducing Oxidative

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This dataset allowed the researchers to investigate differential expression of mitochondrial-related genes across normal, obese, and diabetic samples, thereby contextualizing their in vitro findings with human disease states [1]

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The main target for Grx2 in mitochondria is Complex I, although UCP3 and the 2-oxoglutarate dehydrogenase (OGDH) have been also shown to be deglutathionylated by Grx2