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Within the DRUG table, medications are systematically classified into four causality categories: Primary Suspect (PS), Secondary Suspect (SS), Concomitant (C), and Interacting (I)

Additionally, GLP-1 medications are associated with gastrointestinal side effectsincluding nausea, vomiting, diarrhoea, and constipationwhich can affect nutritional intake and hydration status

The generated OTU table was filtered by removing singletons as well as low-confidence OTUs which, which underwent bleed-through removal between MiSeq runs

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The oral melanotic macule is a flat brown mucosal discoloration produced by focal increase in melanin deposition or a concomitant increase in the number of melanocytes