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Peter Lurie, a former FDA official who now directs the Center for Science in the Public Interest, described allowing peptides to market without clinical testing as a "profound threat" to the FDA's decades-long drug vetting system

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Serious but uncommon events reported in trials or post-market include: Pancreatitis Gallbladder disease Acute kidney injury related to: Volume loss Allergic reactions Hypoglycemia can happen when tirzepatide is combined with insulin or certain oral diabetes drugs

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