Gene expression analysis in ARPE-19 cells was conducted by amplifying the following genes: SOD2 (protein name: superoxide dismutase 2, mitochondrial), CAT (protein name: catalase), HMOX1 (protein name: heme oxygenase 1), SNAL1 (protein name: Snail Family Transcriptional Repressor 1), ZEB1 (protein name: Zinc finger E-box-binding homeobox 1), TWIST1 (protein name: Twist Family BHLH Transcription Factor 1), VIM (protein name: Vimentin), FN1 (protein name: Fibronectin 1), ACTA2 (protein name: actin alpha 2, smooth muscle) and GAPDH (protein name: glyceraldehyde-3-phosphate dehydrogenase)
Nat Protoc 1 , 31593165 (2006)
DHEA DHEA, i.e., dehydroepiandrosterone, is one of the most abundant steroids in your body
In a clinical sample of 1,397 women, researchers examined whether blood vitamin D levels were associated with PCOS adjusting for age, BMI, smoking, alcohol
Both drug therapies significantly reduced levels of oxidized glutathione (GSSG), 8-hydroxy-2-deoxyguanosine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA), while amlodipine also reduced 13-hydroxy octadecadienoic acid (13-HODE) levels