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GLP-1 also signals the brain to induce satiety (the feeling of being full) and slows down the rate at which the stomach empties, thus reducing hunger and controlling food intake
They are also used clinically in some liver and immune support contexts, always under medical supervision
Neither semaglutide nor orlistat has a strict upper limit for how long it can be used
By pairing GLP-1 agonists with muscle-preserving agents targeting pathways like myostatin/activin, apelin and mTOR, companies hope to drive fat loss while maintaining lean muscle tissue
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