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A 2025 study compared the effectiveness of tirzepatide and semaglutide in patients with obesity

78,79 This suggests that, under appropriate signals, both -cells and aged -cells could be reprogrammed to perform the roles of insulin-producing cells

While the FDA-approved prescribing information does not list sexual dysfunction as a recognized side effect, some patients report changes in libido during treatment

Commonly reported side effects include: Nausea or queasiness Reduced appetite Digestive changes Dry mouth Metallic or altered taste sensations These effects vary by individual, dosage, and duration of treatment

storage is governed by the IMP label, the sponsor's Pharmacy Manual, and GCP guidelines, with the trial site pharmacist as the definitive authority