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Studying gastrointestinal protection, gastric or hepatic ischemia, or general cytoprotection

We further examined the contributions of IGF-1R and IL-6/STAT3 pathways using reporter assay

It would also help explain a clinical observation discussed later: the gastrointestinal side effects associated with amylin analogs (nausea, early fullness) tend to be most pronounced during dose escalation and to ease with continued treatment, a pattern consistent with partial adaptation of the very gastric mechanism in question

Obesity (Silver Spring), 30(6), 10401051