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First, the 0.25mg starting dose is not a therapeutic dose

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We do not recommend air travel: For domestic flights within 48 hours of polyp removal For long-haul flights or travel to remote areas within 5 days if a polyp has been removed and ideally not for the full 14 days Are there alternatives to colonoscopy

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Owing to a magnesium block at hyperpolarized potentials, opening of NMDAR channels requires both binding of glutamate to the receptor and depolarization to relieve the pore from magnesium block