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In another study, rats fed a selenium-deficient diet exhibited low sulfotransferase activity, which resulted in diminished contents of sulfated glycosaminoglycan essential for mechanical stress-absorbing property of cartilage matrix 28

Abstract Irritable bowel syndrome (IBS) is the most common functional bowel disorder worldwide and is associated with visceral hypersensitivity, gut motility, immunomodulation, gut microbiota alterations, and dysfunction of the brain-gut axis

Integration into clinical practice will rely on forthcoming phase III data, cost-effectiveness analyses, and evolving guidelines

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