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It involves not just nerves, but hormones and the guts own nervous system, the enteric nervous system

14,15 It is helpful to first ask permission to discuss weight, review past experiences with weight management, and use person-first language to emphasize that people are not defined by their condition (e.g., a patient has or lives with diabetes or obesity, rather than a diabetic or obese patient)

In 2022, a novel GLP-1 analog, semaglutide was introduced as an anti-obesity drug

GLP-1 infusion slows gastric emptying of solid and liquid components of food and alters the distribution of food in the stomach so that a greater proportion of food is retained in the distal stomach (Marathe et al., 2011)

Higher doses tend to trigger stronger side effects