It activates melanocortin receptors MC1R and MC3R, suppressing NF-kappaB nuclear translocation and consequently reducing pro-inflammatory cytokine production including TNF-alpha, IL-6, and IL-1beta
Prescription-grade topical science, not a department store cream
Trends Mol Med 24(9):74862 Vallv-Juanico J, Santamaria X, Vo KC, Houshdaran S, Giudice LC (2019) Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease
This matters because sterility failure isnt a cosmetic issue
Thus, recently, there have been many online advertisements about self-tanning products that contain MT2