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We hope that our work will bring more attention to how organelles and their metabolites are relevant to cancer biology, says Kivan Birsoy, head of the Laboratory of Metabolic Regulation and Genetics at Rockefeller
However, given that we have a significant lack of non-invasive treatment options, Im certainly open to ideas and pilot studies
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We observed significant changes in ER-associated proteins, including redox-responsive enzymes and chaperones (e.g., TXNDC5, CALU, CANX, ERP44, and PARK7)
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