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While individuals with some monogenic causes, such as Angelman Syndrome (AS), Fragile X Syndrome (FXS), and Rett Syndrome (RTT) [8,9,10], have features of ASD, the etiology of ASD as a whole is extremely heterogeneous [11, 12]

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Chronic alcohol use can lead to increased glutamate release and decreased GABA signaling, resulting in a hyperexcitable state that may contribute to anxiety and depressive symptoms (Hansen et al

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