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The FDA does not approve compounded medications for safety, quality, or manufacturing

Dual inhibition of excitatory and inhibitory neurotransmission to cardiac vagal neurons likely differentially affects their activity based on the combination of active physiological reflex pathways at any given time

[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Splinter M.Y

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These detrimental effects appear to be dose-dependent and are more pronounced when antioxidant supplementation is absent