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The presentation of the PR3 autoantigen on the cell membrane (mPR3) of neutrophils and monocytes is pivotal for PR3-AAV

doi: 10.1038/nm.3681 57 ChaoCCGutierrez-VazquezCRothhammerVMayoLWheelerMATjonECet al

coli by SEC (among many other biophysical techniques) it was concluded that permuteins, being intrinsically disordered, are characterized by high compactness degree, as evidenced by their Stokes radii exceeding those of globular proteins with the same molecular weight by a factor 1.2 (Uversky et al., 1996), which is a characteristic feature of the molten globule-like folding intermediate of globular proteins (Uversky, 1993

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