The Digital Scholars in Practice Series (DSIP) highlights the work of scholars conducting research through digital technologies and critically examining digital technologies in practice
The 12 mg row is included for completeness because the Phase 2 trial escalated through 1 mg, 2 mg, 4 mg, 8 mg and 12 mg arms, with the 12 mg cohort reaching approximately 24.2% mean weight loss at 48 weeks at the cost of a heavier nausea and constipation burden [2][5]
This depletion can weaken the immune response, allowing the parasites to thrive
DSIP promotes sleep in a species-specific manner, with varying effects on different types of sleep across species
The resulting oxidized form of GSH either reacts with another GSH molecule to form GSSG or with cysteine groups on cellular proteins to form protein GSH mixed disulfides, a process known as protein glutathionylation. This latter reaction can change the proteins structure and function, which can, in turn, evoke a functional change within the cell