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Suitable water soluble buffering agents are alkali or alkaline earth metal carbonates, phosphates, bicarbonates, citrates, borates, acetates, succinates and the like, such as sodium phosphate, citrate, borate, acetate, bicarbonate, carbonate and tromethamine (TRIS)

Unlike Palisek's earlier design, which was larger, centrally located on the device and used domed switches, Nintendo's version was smaller, positioned for the left thumb, and employed membrane switches that were easier to depress

This suggests that further research is warranted

10.1038/35067088 Nat Rev Mol Cell Biol

Align DSNPs and MLTSS Programs: DSNP contracts can be used to align a state's Medicaid managed care plans, including MLTSS plans, with DSNPs operating in the state by requiring the entities offering Medicaid plans to also offer companion DSNPs covering the same geographic area, or conversely , by requiring the entities offering DSNPs to offer MLTSS plans