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Adding oral semaglutide (Rybelsus) as a bridge

In contrast, prolonged treatment with the GLP-1 receptor agonist semaglutide lowered perfusion compared with placebo (41)

Back Finan, B, Ma, T, Ottaway, M (20 Oct 2013) 'Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans', Science Translational Medicine , 5/209, 2-9a151

2025;4:EVIDoa2500158

Encouraging patients to track symptom changes can help clarify whether improvements correlate with weight loss, glycemic control, or medication timing