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ICAM 1, intercellular adhesion molecule 1
pneumoniae in host cells To assess levofloxacin persistence of pneumococci, A549 and RAW 264.7 cells infected with pneumococci (as described above) were maintained in DMEM supplemented with 1% FBS and 6 mg/mL levofloxacin, while PLB-985 and PLB-985 nox2 -KO infected cells were cultured in RPMI 1640 with 1% FBS, 1.3% DMSO, and 6 mg/mL levofloxacin
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Interestingly, these pharmacological concentrations align closely with peak levels of endogenous GLP-1 observed during intense physiological stimulation [120, 121]
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