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Long-Term Safety Unknown: Most studies are under 30 days

The Journal of clinical endocrinology and metabolism 99 , E13061310, (2014)

Naturally, this raises the question of whether dosing has been optimised at the ideal sweet spot where efficacy, safety and cost are all in balance, and there is the best chance of long-term persistence

In another study in volume-loaded participants, GLP-1 induced natriuresis together with the ANG II level decrease, independent of renal hemodynamics (renal plasma flow, GFR unchanged) and renin concentrations 37

Prior Authorization Requirements In states where Medicaid does cover weight loss shots, prior authorization (PA) is almost universally required