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oral formulation (Rybelsus) also available Lixisenatide (Lyxumia) once-daily injection NICE guidance for type 2 diabetes (NG28) recommends GLP-1 receptor agonists in specific circumstances: typically as a third-line option when other treatments haven't achieved adequate glycaemic control, particularly in people with a BMI 35 kg/m (adjusted for ethnicity), or for whom weight loss would benefit other obesity-related comorbidities, or for whom insulin would have significant occupational implications
doi: 10.1530/JOE-24-0210 67 AkyayOZCanturkZSelekACetinarslanBTarkunCakmakYet al
About 10%-25% of patients with NAFLD will develop non-alcoholic steatohepatitis (NASH), which increases the risk of liver cirrhosis or liver cancer (185)
These reports can show possible safety signals, but they do not prove that a drug caused a specific injury in every case
This begs the question what is the real problem the food noise or the restriction which is fueling the food noise
