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10.1152/ajpgi.00223.2019 76

Activation of the HIF-1 pathway in SDH-deficient tumors is most likely the result of accumulating levels of succinate which is then transported into the cytosol via the action of the mitochondrial dicarboxylate transporter

And its incredibly vulnerable during this transition

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On this episode of #AskUSADA, Operations and Special Projects Director, Juan Caraveo, discusses how doping control officers can assist athletes during sample collection