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10.1002/smll.202502577 Summary Keywords cell signaling-target, clinical transition, immune cell activation, nanomedicine, photothermal therapy, two-domensional nanomedicine Citation Deb VK, Mukherjee A, Pathak S, Paul S, Duttaroy AK and Adhikari S (2026) Advancements in nanomedicines for cancer therapy: targeting molecular signaling pathways, activating immune cells, and using photothermal immunomodulation