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Similarly, in a diabetic rat model induced by a high-fat diet and streptozotocin (STZ) injection [54, 55], liraglutide was shown to mitigate the hyperglycemia-induced decline in RGC-5 cell viability and improve the structural integrity and organization of the GCL [56]

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The metabolic adaptations observed are largely consistent with weight loss achieved through any method, rather than being unique effects of GLP-1 medications themselves

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