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Approval: 2004 Indications and Usage for Pemetrexed Injection Pemetrexed Injection is a folate analog metabolic inhibitor indicated: in combination with pembrolizumab and platinum chemotherapy, for the initial treatment of patients with metastatic non-squamous non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations

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PEH can also present acutely with complications: bleeding, acute obstruction, and strangulation resulting in gastric necrosis [3]