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VanderSpek J

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The following situations are particularly risky: - Long-term use of very high-dose preparations (from 1,000 g daily for months/years) without medical supervision

FIGURE 4 Cyclization of peptides is a strategy that can make peptides have a more stable conformation, enhancing the stability of enzymatic proteolysis and improving the permeability through biological barriers (Karami et al., 2023)