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Mood Changes Changes in mood including feelings of sadness or irritability can sometimes be linked to low vitamin B12 levels

Of the remaining 45 articles, 6 full texts could not be retrieved and 14 were excluded as they were out of scope

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and c) irregular dietary patterns), reduced bioavailability (impairment of the intrinsic factor-mediated absorption pathway, often due to the widespread and prolonged use of proton pump inhibitors), and malabsorption syndromes

Improving insulin sensitivity can also help manage high blood pressure, reducing the risk of heart disease