Lastly, through a genome-wide CRISPR loss-of-function screen, we confirmed that the effects of LCS3 are related to antioxidant response and found that inactivation of NADPH quinone oxidoreductase 1 (NQO1) impairs ROS production and confers resistance to LCS3
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And then of course, there's going to be the, I don't want to call it placebo, but there's going to be the context, the conditioned place context of it
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All experiments were performed in accordance with the University of Alberta institutional guidelines, which conformed to guidelines published by the Canadian Council on Animal Care and the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health (revised 2011)
