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For BP labeling with different additives, each component was added with following concentrations: 5%, 10% and 15% FBS

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Cells synthesize acrolein through various metabolic pathways, including the metabolism of polyamines such as spermine and spermidine by amine oxidase, the breakdown of threonine by neutrophil-derived myeloperoxidase, the breakdown of cancer drugs such as cyclophosphamide, and the lipid peroxidation of polyunsaturated fatty acids (PUFAs) (110, 112)

When the hypothalamus perceives the body as too warm, it triggers a response to dissipate the heat, resulting in a hot flash