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Newer drugs like Retatrutide could potentially deliver better outcomes because they target multiple hormones simultaneously.

In summary, our urine results indicate that weight loss through GLP-based therapies is not associated with prolithogenic changes in 24-hour urine chemistry in patients with nephrolithiasis, unlike what happens with alternative weight loss modalities (such as malabsorptive bariatric surgery and pharmacological therapy with orlistat or topiramate)

L., RoyChoudhury, A., & Laferrre, B

Recent research shows that GIP directly regulates the brain's hunger neurons after you eat