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As described, the cGAS-STING pathway is a canonical in innate inflammatory stress responses, not only within neurons and glial cells of the CNS but also across a broad range of peripheral tissues, contributing to diverse pathological contexts such as cancer (Chakraborty et al., 2024
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Previous reports have shown the reduction of aldehydes into alcohols using NADH as a hydride source 15 , NAD + into NADH using formate as a hydride source 16 , pyruvate into lactate using formate as a hydride source 17,18 , or ally alcohols into ketones 19
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