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Br J Pharmacol 166: 27-41, 2012

GLP-1 drugs are promising in some areas and need more research in others

In this research, we treated mouse zygotes with a low concentration (0.03 mM) of H 2 O 2 to create a model strongly recapitulating the clinically observed phenomenon of oxidative damage in IVF embryos and found that the ROS level in the H 2 O 2 /EGCG-treated group was close to that in the EGCG-treated group and that the total cell numbers of IVF blastocysts in both groups were nearly 1.5-fold higher than that in the control group

in addition, chronic accumulation of such metals is known to increase the risk for neurodegenerative disorders, particularly of AD and PD

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