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UPS-dependent strategies of protein quality control degradation

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The use of metals to restore the normal healthy physiology of the body either by direct administration of essential metals, or by chelating out excess or toxic metals, or using them as carriers for targeted drug delivery, or for tagging biomolecules for diagnostics, are all techniques that may be classified under the general heading of metallo-pharmacology

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A thoughtful research program may employ all three and this peptide is often the entry point because its effects are the most rapidly measurable and the most visually apparent