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Exenatide is a GLP-1 analog, derived from exendin-4 and originally isolated from the salivary secretions of the Gila monster [26]

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(26) This retrospective cohort study included 74,475 patients with type 2 diabetes taking either an SGLT2-I, GLP-1, or sulfonylurea, with sulfonylureas serving as the reference group

Pharmaceutical companies are investing in next-generation analogues with extended half-lives, improved bioavailability, and once-weekly or even monthly dosing regimens